Search Results - DNA

Amino Acid Alterations in Sperm Linked to Infertility

Crédito: https://unsplash.com/photos/1NvNQIYToic Sperm play a vital role in creating new life, contributing half of the required genetic material for fertilization. Researchers at the University of Michigan are now delving into the molecular-level details of sperm formation, focusing on protamines—a unique group of proteins that package sperm DNA. Understanding the significance of protamines may shed light on...

Unraveling the Activation Process of a Key Protein with Therapeutic Potential

Credit: Unsplash. Scientists have achieved a significant breakthrough by uncovering the step-by-step activation process of a protein with deep evolutionary roots found across all domains of life. This discovery opens up new possibilities for utilizing the protein as a powerful biotechnology tool with potential applications in therapeutics. Argonaute Protein and RNA Interference The protein in focus belongs to...

Revealing the Biology of Insulin Production

Credit: iStock. The finding of insulin has been a life-saving breakthrough for countless individuals suffering from diabetes worldwide, yet there remains limited knowledge about the initial stages of insulin production. However, university of Michigan researchers have made progress in understanding a crucial aspect of insulin production. By examining messenger RNAs involved in insulin synthesis in fruit...

Combination Therapy a One-Two Punch to KO Aggressive Brain Cancer

Credit: Unsplash. A recent research investigation revealed that the combination of radiotherapy and a virus designed to target cancer cells proved to be more successful in treating a challenging and fatal type of brain tumor compared to the individual use of either therapy. The National Brain Tumor Society reports that glioblastoma (GB) constitutes slightly more than half,...

Evolutionary Fuel: Researchers Study Maintenance of an Ancient Chromosomal Inversion

Stick insects, Timema knulli, on a Redwood tree branch. Utah State University evolutionary geneticist Zach Gompert and colleagues studied a chromosomal inversion in the species and report findings in the June 12, 2023, online edition of PNAS. Credit: Moritz Muschick. According to Zachariah Gompert, an evolutionary geneticist from Utah State University, genetic diversity serves as the...

Crocodile’s ‘Virgin Birth’ is a First for Science’s History Books

An image of a crocodile. Credit: Ray Bilcliff/ Pexels Throughout history, tales of virgin births, which involve the production of offspring without fertilization, have been shared. Examples of such stories include the birth of Mars, an ancient Roman god, Horus, an ancient Egyptian god, and Qi, a figure from ancient Chinese mythology, all of whom...

Modified Eggs May Lead To The End Of Allergies

Scientists have utilized genome editing technology to create a chicken egg with reduced allergenic properties. Image Credit: Canvas Allergies to eggs are highly prevalent among children and can be provoked by various food items, including vaccines. However, scientists have recently utilized genome editing technology to create a chicken egg that could potentially be consumed by...

New Antibiotic Cures Superbugs Without Bacterial Resistance

Credit: Canva In a potential game changer for the treatment of superbugs, a brand-new class of antibiotics was developed that cured mice infected with bacteria regarded virtually "untreatable" in humans-- and resistance to the drug was undetectable. Produced by a research team of UC Santa Barbara researchers, the research study was released in the journal eBioMedicine....

New Class of Medicinal Compounds that Target RNA

Graphical abstract. Credit: Biochemical and Biophysical Research Communications (2022). DOI: 10.1016/j.bbrc.2022.12.080 A team of undergraduate and also graduate chemistry students in Jennifer Hines' laboratory at Ohio University recently uncovered a current class of compounds that can target RNA and disrupt its function. This discovery determined a chemical scaffold that might ultimately be utilized in the development of...

Scientists Clarify Role of Blood Cell Mutations in Illness

Credit: CC0 Public Domain More than 10% of older adults create somatic (non-inherited) mutations in blood stem cells that could trigger explosive, clonal expansions of abnormal cells, enhancing the risk for blood cancer and heart disease. Multiple DNA sequencing techniques have been utilized to determine what is called "clonal hematopoiesis of indeterminate potential," or CHIP. Still,...