People with higher muscle mass appear to exhibit reduced indicators of brain aging, according to newly released research. The study, which is still awaiting peer review, appears at the yearly conference of the Radiological Society of North America (RSNA).
The study raises concerns that GLP-1 drugs like Ozempic, Wegovy, and Mounjaro may reduce both fat and muscle mass.
The study examined MRI scans from 1,164 healthy adults with an average age of 55. Researchers compared brain structure measurements with full-body imaging and noted that…
Muscle Mass Linked to More Youthful Brain Aging
The researchers discovered that people with higher muscle mass had “younger”-looking brains, and that having less visceral fat relative to muscle was likewise linked to reduced brain aging.
Initially developed for managing type 2 diabetes, GLP-1 drugs have since gained widespread use for quick weight loss.
However, earlier research has shown that roughly 15% to 40% of the weight shed while using these drugs can be lean mass, including muscle.
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