Polymyxins Turn Cell Membranes Into Breakable Crystals
Polymyxin “last-resort” antibiotics kill bacteria by crystallizing their cell membranes. Credit: TED HOROWITZ/THE IMAGE BANK/GETTY IMAGESTo eliminate drug-resistant bacteria, "last-resort" antibiotics borrow a method from Medusa's playbook: petrification.New high-resolution microscope pictures show that a class of antibiotics called polymyxins crystallizes bacteria's cell membranes. The honeycomb-shaped crystals that form transform the microorganisms' normally supple skins...