We all have heard of Africa as the "cradle of humankind" or the "fountain of humankind”, due to the earliest evidence of human ancestors found here. A new research show on how the African ancestor mixture and a couple of truths on how they lived and connected came to light.A group of 44 researchers...
Credit: Unsplash.Research team leader Joanne Cole, Ph.D., an assistant professor in the Department of Biomedical Informatics at the University of Colorado School of Medicine, stated that they have identified genes associated with sensory pathways, including taste, smell, and texture, which may also impact the brain's reward response.However, these genes could potentially be utilized...
illustration of the structure of DNA. Credit: Unsplash.A recent study led by researchers at Weill Cornell Medicine and the National Heart, Lung, and Blood Institute, a division of the National Institutes of Health, has found that DNA has the ability to imitate protein functions by adopting intricate and three-dimensional structures.A recent study, published in...
Astronaut in space. Credit: Unsplash.In the realm beyond Earth, the absence of gravity poses a significant hazard to the well-being of astronauts, particularly during extended missions. Gaining insights into the response of the human body to the space environment is essential for long-term space exploration and the development of countermeasures to safeguard astronaut health.Previous...
Stick insects, Timema knulli, on a Redwood tree branch. Utah State University evolutionary geneticist Zach Gompert and colleagues studied a chromosomal inversion in the species and report findings in the June 12, 2023, online edition of PNAS. Credit: Moritz Muschick.According to Zachariah Gompert, an evolutionary geneticist from Utah State University, genetic diversity serves as the...
In the initial comprehensive study conducted on monkeys, it was discovered that CRISPR does not induce unintended off-target mutations. Credit : galitskaya/Depositphotos.As the first human trials utilizing the potentially groundbreaking CRISPR gene editing technique are set to begin in the UK and the US, there are lingering concerns regarding the overall safety of this...
Great white shark Credit: https://www.pexels.com/pt-brGreat white sharks have few predators capable of dominating them. Yet their lives are not easy as they have to deal with others of the same species.Even having terrible wounds in a short time, white sharks can heal and this characteristic we also find in other species of sharks.In...
Credit: Unsplash/CC0 Public DomainIn a research showing up today in JAMA Network Open, Rady Kid's Institute for Genomic Medicine (RCIGM) scientists discovered that the contribution of genetic diseases to infant deaths was greater than formerly recognized. Of 112 infant deaths examined, single-locus (Mendelian) genetic diseases were found to be the most typical antecedent of...
Atherogenesis is depicted in a young (a) or aged (b) host. Aged monocytes/macrophages have decreased levels of the epigenetic regulator TET2, leading to reduction of the 5-hydroxymethylcytosine (5hmC) mark on the Itgb3 promoter. The resulting low integrin β3 levels in aged monocytes/macrophages induces high TNFα levels, facilitating recruitment and expansion of multiple SMC progenitors...
Credit: CC0 Public DomainMore than 10% of older adults create somatic (non-inherited) mutations in blood stem cells that could trigger explosive, clonal expansions of abnormal cells, enhancing the risk for blood cancer and heart disease.Multiple DNA sequencing techniques have been utilized to determine what is called "clonal hematopoiesis of indeterminate potential," or CHIP. Still,...
