Found in Vietnam and Cambodia Mosquitoes Extremely Resistant to Insecticides

Found in Vietnam and Cambodia Mosquitoes Extremely Resistant to Insecticides

Primal dengue mosquito vector, Aedes aegypti, which have shown extremely high level of insecticide resistance in Asia due to concomitant mutations. Credit: Shinji Kasai

Mosquitoes extremely resistant to common insecticides

A group of scientists affiliated with many institutions in Japan, working with associates from Vietnam, Cambodia, Singapore, Taiwan, Indonesia, and Ghana, has discovered proof of mosquitoes that are extremely resistant to typical insecticides in Vietnam and also Cambodia.

Insects like mosquitoes carry a host of infectious illnesses, ranging from dengue and yellow fever to the Zika virus and malaria. So, researchers have created a host of chemicals aimed at eliminating or repelling mosquitoes, most of which are named pyrethroids and target the mosquito’s central nervous system. In this new effort, the scientists have discovered proof of mosquitoes in Vietnam and Cambodia evolving to become extremely resistant to pyrethroids.

Collecting Mosquito Samples for Research

The work involved going to the field and gathering mosquitoes in Vietnam, Indonesia, Ghana, and Taiwan. The scientists after that sprayed each of the samples with permethrin, a pyrethroid that is typically utilized in all of the locations where the samples were collected. They discovered that simply the 20% of the mosquitoes gathered from Vietnam perished. Death rates from mosquitoes in the other samples were as expected.

The scientists then looked at the genomes of the mosquitoes which had survived exposure to the insecticide and discovered a mutation in the L982W gene– a gene that has already been connected to resistance in mosquitoes. The group, after that, gathered more samples, this time from Singapore and Cambodia, and analyzed their genes, looking specifically at L982W. They discovered ten unique strains with mutations similar to those seen in the Vietnamese mosquitoes– and almost all of them were in Cambodia.

The researchers estimated that approximately 78% of the mosquitoes in the samples they gathered from Cambodia or Vietnam were resistant to pyrethroid– and those with the pyrethroid mutation were found to have on average a 50- to 100-fold increase in resistance. They also searched for combinations of mutations that guide to resistance and discovered that those with a combination of L982W and other mutations could survive pyrethroid exposure degrees of 500 to 1,000 times more than the quantity that typically kills mosquitoes.

The scientists conclude that other countries should start testing for resistance to determine the true magnitude of the issue.


Read the original article on PHYS.

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