Recipient of Historic Pig Kidney Transplant Passes Away

The initial successful transplantation of a genetically modified pig kidney into a human recipient continues to be celebrated as a significant medical breakthrough and achievement, despite the unfortunate passing of the recipient.

Massachusetts General Hospital (MGH), where 62-year-old Richard “Rick” Slayman underwent the groundbreaking procedure, clarified that his passing isn’t attributed to kidney failure, as per the surgical team’s statement.

MGH Statement on the Passing of Mr. Rick Slayman

“The Mass General transplant team mourns the unexpected loss of Mr. Rick Slayman,” read the statement from MGH. “We have no evidence indicating it resulted from his recent transplant.

Mr. Slayman will forever symbolize hope for numerous transplant patients globally, and we profoundly appreciate his confidence and commitment to advancing the field.”

We previously reported on his surgery on March 16, a moment of optimism for both patient and medical team. Slayman showed remarkable progress, walking around within days of receiving his new kidney, which was projected to function for approximately two years.

This transplant allowed him to discontinue the debilitating dialysis treatment he had been undergoing three times a week, following complications from a 2018 human kidney transplant that led to its removal last year. Slayman suffered from end-stage kidney disease and congestive heart failure.

Highlighting the Significance of Groundbreaking Xenotransplantation

While the cause of death remains undisclosed, his family emphasized in a statement that the groundbreaking surgery represents a positive step forward in xenotransplantation. Researchers aspire to address the critical shortage of human organs by successfully transplanting genetically modified non-human animal organs.

In the United States alone, around 90,000 individuals are on the kidney transplant waiting list, and many will perish before a suitable organ becomes available.

“Rick stated that one of his motivations for undergoing the transplant was to offer hope to the thousands in need of transplants to survive,” expressed Slayman’s family in their statement.

“He achieved this goal, and his hope and positivity will remain everlasting. His legacy will serve as an inspiration to patients, researchers, and healthcare professionals worldwide.”

eGenesis, the Boston biotech firm responsible for modifying Slayman’s pig kidney by altering genes for compatibility and deactivating retroviruses, also honored his memory.

“Mr. Slayman was a true trailblazer,” eGenesis shared on social media on May 11. “His bravery has paved the way for current and future patients battling kidney failure.”

On April 12, Lisa Pisano, a 54-year-old from New Jersey facing heart and kidney failure, became the second successful recipient of a genetically modified pig kidney. This followed her recent mechanical heart implant. In her case, the kidney she received had undergone only one genetic alteration.

The Legacy of Pioneering Xenotransplantation

Slayman’s family emphasizes that the pioneering surgery, which extended his life, was a gift—for both his loved ones and the advancement of xenotransplantation.

“We are deeply saddened by the unexpected loss of our dear Rick but find solace in knowing he inspired many,” they added. “Rick’s story has touched millions worldwide. Despite our grief, we find comfort in the hope he instilled in patients anxiously awaiting transplants.”

“To us, Rick was a compassionate individual with a sharp wit, deeply committed to his family, friends, and colleagues,” they remarked, expressing gratitude to the dedicated surgical team.

“Their tireless work in pioneering xenotransplantation afforded our family seven additional weeks with Rick, and the cherished memories created during that time will endure in our thoughts and hearts.”

To conclude, The sentiment was shared by the MGH team, who stated, “We extend our sincere condolences to Mr. Slayman’s family and loved ones as they commemorate an exceptional individual whose generosity and warmth touched the lives of all who knew him.”

Read the original article on: New Atlas

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