Cell Biology

Protein “Big Bang” Reveals Molecular Makeup for Medicine as well as Bioengineering Applications

Research by Gustavo Caetano-Anollés and Fayez Aziz, University of Illinois, reveals a “big bang” during evolution of protein subunits known as domains. The team looked for protein relationships and domain recruitment into proteins over 3.8 billion years across all taxonomic units. Their results could have implications for vaccine development and disease management. Credit: Fred...

Advanced Cryo-EM Exposes Viral RNA Duplication Complex Structure in “Game-Changing” Detail

Cryo-EM imaging reveals high-resolution side and top views of the viral RNA replication “crown” complex structure. Credit: Paul Ahlquist, Morgridge Institute for ResearchFor the very first time, researchers at the Morgridge Institute for Research have created near-atomic resolution images of a significant viral protein complicated responsible for replicating the RNA genome of a member...

Researchers Discover “Gorditas” and Other Unheard Types of Brain Cells

The newly described oligodendrocyte progenitor cells (green) contact long-distance neuronal axons (magenta) on the wall of the brain ventricles.According to a study published June 20 in Science, scientists discovered two types of glial cells in the brains of adult mice - an astrocyte and an oligodendrocyte progenitor cell - after pushing neural stem cells to...

“Inescapable” COVID-19 Antibody Discovery – Neutralizes All Known SARS-CoV-2 Strains

An artistic rendering of antibodies surrounding a SARS-CoV-2 particle. Credit:  LAWRENCE BERKELEY NATIONAL LABORATORYAn antibody treatment that seems to reduce the effects of all recognized SARS-CoV-2 pressures and various other coronaviruses was created with some help from architectural biologist Jay Nix.Lifesaving COVID-19 injections are enabling us to feel optimistic once again, after over a...

MIT Researchers Devised a Means to Program Memories Into Microbial Cells by Revising Their DNA

MIT researchers have devised a way to program memories into bacterial cells by rewriting their DNA more efficiently. Credit: MIT News, iStockphotoOrganic engineers at MIT have created a brand-new way to edit bacterial genomes successfully and program memories right into microbial cells by revising their DNA. Using this technique, various spatial and temporal information...

Neurotransmitter Levels in the Brain Can Predict Math Ability

Scanning was completed both during Time 1 and Time 2 (approximately 1.5 years later) in each of the 5 age groups (6-year-olds, 10-year-olds, 14-year-olds, 16-year-olds, and 18+-year-olds). Credit: Zacharopoulos G, et al., 2021, PLOS Biology, CC-BY 4.0The neurotransmitters GABA and glutamate have complementary functions - GABA inhibits neurons, while glutamate makes them extra active. Published...