Search Results - metabolic

New Class of Medicinal Compounds that Target RNA

Graphical abstract. Credit: Biochemical and Biophysical Research Communications (2022). DOI: 10.1016/j.bbrc.2022.12.080 A team of undergraduate and also graduate chemistry students in Jennifer Hines' laboratory at Ohio University recently uncovered a current class of compounds that can target RNA and disrupt its function. This discovery determined a chemical scaffold that might ultimately be utilized in the development of...

Belt and Suspenders: Alpine Lake Bacteria Deploy 2 Light-Harvesting Systems

Lake Gossenköllesee is located in the Tyrolean Alps. Credit: Christopher Bellas Though human beings, along with other vertebrate and invertebrate organisms, do not photosynthesize, we're certainly the downstream beneficiaries of the life forms that do. Phototrophic organisms at the bottom of the food chain convert plentiful sunlight into the energy that ultimately powers all other...

New Research Discovers Links Between Genetic Factors in Autism Spectrum Disorder (ASD)

Credit: Unsplash/CC0 Public Domain In a recent research released today in Cell Reports, scientists from the Donald K. Johnson Eye Institute (DKJEI), part of the Krembil Research Institute at University Health Network, have determined anteriorly unknown links between genetic factors in autism spectrum disorder (ASD). This neurodevelopmental disorder  is associated with a wide variety of physiological...

Cholesterol and Diabetes Drugs May Reduce the Danger of Degenerative Eye Illness

Normal usage of drugs to reduced cholesterol and control kind 2 diabetes may decrease the threat of the degenerative eye illness associated with aging, referred to as AMD, discovers a pooled information analysis of the available proof released online in the British Journal of Ophthalmology. The outcomes show that these common drugs are connected to...

Building Human Muscle Genes in the DNA of Baker’s Yeast

Daran-Lapujade’s lab took human DNA (in red) encoding core functions in muscle cells, and inserted it into the DNA (chromosomes in purple) of a yeast cell (in yellow). The humanized yeast can be used as a tool for medical studies, for example in drug screening and cancer research. Credit: Ella Maru Studio / Pascale...

Mitochondria and the Origin of Eukaryotes

The complex cells of organisms known as eukaryotes, such as the animal cell pictured here, arose more than 1.5 billion years ago. Biologists have long known that back then, one simple, bacteria-like cell engulfed another, and the new arrival settled into its host cell to eventually become what we know as the energy-generating mitochondrion. But...

Why Do Women Feel the Cold more than Men?

A woman feeling the cold inside a house. Credit: iStock. We all have distinct preferences for when it is the correct time to draw out winter blankets. And the thermostat's setup frequently forms the basis of office debates between women and men concerning the "appropriate" temperature for it to be configured. Between the sexes, there is...

Infant Infections May Expand the Possibility of Heart Illnesses Later in Life

A study led by the Murdoch Children Research Institute (MCRI) found that multiple infections in infancy could put adults at a higher risk of heart disease, obesity, stroke, and type 2 diabetes. A possible relation between infant infections and the chance of heart disease has been discovered Newborns have weakened body immune systems. Therefore, they are...

Individual Neurons Can Learn by Predicting Future Activity

Credit: Artur Luczak Humans have been trying to comprehend exactly how the brain works and how it obtains information for centuries. While neuroscientists now have a decent understanding of how different parts of the brain work and what their function is, numerous questions remain unanswered; therefore, a unified neuroscience theory is still missing. In recent years,...