Credit: Mimi Hammad ORNL scientists used quantum biology, AI, and bioengineering to improve CRISPR Cas9 genome editing for microbes, boosting renewable fuel and chemical production. CRISPR is a powerful bioengineering tool, that alters genetic code for improved organism performance or mutation correction. CRISPR Cas9 targets and cleaves specific genome sites using a single guide RNA. Previous...
Credit: iStock. The finding of insulin has been a life-saving breakthrough for countless individuals suffering from diabetes worldwide, yet there remains limited knowledge about the initial stages of insulin production. However, university of Michigan researchers have made progress in understanding a crucial aspect of insulin production. By examining messenger RNAs involved in insulin synthesis in fruit...
Research by Gustavo Caetano-Anollés and Fayez Aziz, University of Illinois, reveals a “big bang” during evolution of protein subunits known as domains. The team looked for protein relationships and domain recruitment into proteins over 3.8 billion years across all taxonomic units. Their results could have implications for vaccine development and disease management. Credit: Fred...
The struggle is real: Sugar and fat form a dangerous diet duoDepositphotos It's not surprising that, overall, we consume excessive amounts of sugar. Researchers have discovered that when our craving for sweetness is satisfied, it is replaced by a sudden inclination for fatty foods, potentially disrupting metabolic functions and contributing to weight issues. Hormonal Mechanism Unveiled...
Neurons. Credit: Unsplash. A research team from the University of Lausanne (UNIL) and the Wyss Center has uncovered a novel class of brain cells that plays a pivotal role in brain function. These cells, possessing hybrid characteristics between neurons and glial cells, are found in various brain regions in mice and humans, offering unique insights into memory,...
Credit: Pixaobay Researchers from Duke University's biomedical engineering department have showcased a novel approach that significantly enhances the performance of machine learning models in the search for new molecular therapeutics, even when utilizing only a small portion of the available data. By employing an algorithm that actively detects gaps in datasets, the accuracy of the...
Credit: Andrea Vierschilling / Pixabay. Ying Gu, professor of biochemistry and molecular biology at the Penn State Eberly College of Science and leader of the research team, stated that the study identified a protein called calcium-dependent protein kinase 32 (CPK32) responsible for chemically modifying one of the proteins in the cellulose synthase complex, thereby regulating...
Credit: CC0 Public Domain More than 10% of older adults create somatic (non-inherited) mutations in blood stem cells that could trigger explosive, clonal expansions of abnormal cells, enhancing the risk for blood cancer and heart disease. Multiple DNA sequencing techniques have been utilized to determine what is called "clonal hematopoiesis of indeterminate potential," or CHIP. Still,...
Credit: Pixabay/CC0 Public Domain A team of neuroscientists led by a College of Pittsburgh Institution of Medicine scientist created a test to spot a new marker of Alzheimer's illness neurodegeneration in a blood sample. A research on their outcomes was released today in Brain. New Biomarker The biomarker, named brain-derived tau, or BD-tau, outperforms...
Credit: Pixabay/CC0 Public Domain The blue antelope (Hippotragus leucophaeus) was an African antelope with a bluish-gray pelt pertaining to the living sable and roan antelopes. The last blue antelope was shot around 1800. Only 34 years after it was first explained scientifically, making it the just large African mammal species that have become extinct in...
