Scientists have proposed an innovative approach to control mosquito populations and combat malaria: adding a drug to human blood that is toxic to insects, so that when mosquitoes feed on this blood, it marks their last meal.The drug in question is nitisinone, and a proof-of-concept study led by a team from the Liverpool School...
Credit: PixabayMany people fear injection needles, especially the large ones required for long-term medications. These drugs often need high doses delivered through thick needles because they contain polymers that form medication depots under the skin. The polymer content can range from 23% to 98% of the injection’s weight, making the process even more daunting.To...
Credit: PixabayThe next generation of GLP-1 receptor agonist drugs is on the horizon, with new weight-loss and diabetes treatments expected to hit shelves by early next year. These advancements follow the success of drugs like Ozempic and Wegovy, signaling a rapid evolution in obesity and diabetes care.Less than five years after the FDA approved...
Credit: PixabayPromising cancer drug dostarlimab is advancing toward broader availability after receiving Breakthrough Therapy Designation from the FDA. This designation aims to expedite its development and market approval, potentially cutting years off its timeline if further testing is successful.Dostarlimab (Jemperli), a PD-1-blocking antibody, showed groundbreaking results in clinical trials, eliminating rectal cancer tumors without...
Scientists have engineered skin-dwelling bacteria to produce their own anti-acne drugs. Credit: PixaobayResearchers have shown a novel approach to combat acne by genetically modifying skin bacteria to produce proteins present in acne medications, highlighting a potential breakthrough in acne treatment.Acne initiates when hair follicles become obstructed with a combination of dead skin cells and...
The medication fights against carbapenem-resistant Acinetobacter baumannii, a challenging human pathogen that eludes the majority of antibiotics. Credit: Unsplash.An antibiotic belonging to a novel class of drugs has recently been uncovered, offering potential effectiveness against a major bacterial threat to human health. The antibiotic, named zosurabalpin, has exhibited promising results in laboratory experiments and...
This diagram outlines the various phases of the analysis process, encompassing the creation of interaction graphs derived from X-ray structures. These graphs are instrumental in training and testing a Graph Neural Network (GNN) to forecast numerical affinity values. The subsequent steps involve pinpointing the significance of edges in making predictions and identifying subgraphs that...
Credit: Lung Disease NewsA current advancement publication by researchers at the Masonic Medical Research Institute has discovered a novel way of treating pulmonary fibrosis. This progressive, incurable disease leads to the stiffening of the lungs through scarring, using nanoparticles.However, nano drug delivery is a promising field that offers significant possibilities for the treatment of...
(Shubhangi Ganeshrao Kene/Science Photo Library/Getty Images)Alagille syndrome is a potentially deadly genetic disorder that affects numerous organs and systems, most notably the liver. Currently, there's no known treatment for it-- however, researchers have now identified a potentially effective therapy.Called NoRA1, the newly developed drug targets the Notch pathway, a cell-level signaling system in the...
