The Drops That Could Save Your Life
At present, the timely administration of treatment within a few hours of experiencing a stroke is critical for favorable recovery outcomes. However, in the future, this may change with the introduction of newly developed nasal drops, which offer the possibility of improved chances of recovery even if immediate medical intervention is not available.
The nasal drops consist of a naturally occurring peptide called C3a, which is produced in the central nervous system. Earlier studies have indicated that this peptide has the potential to aid in the restoration of motor function among individuals who have experienced a stroke.
The Drops On Mice
In the ongoing study, mice that had suffered a stroke were administered the nasal drops seven days after the incident. Comparisons with a control group that did not receive the treatment revealed that the mice who received the drops exhibited faster and more extensive recovery of motor function.
Furthermore, the MRI scans of the mice’s brains revealed a notable increase in the development of new connections between nerve cells. Additionally, the introduction of C3a through the nasal drops appeared to enhance the functionality of astrocytes, which play a role in regulating certain functions of nerve cells.
The Drops Positive Impact On Patients
The positive impact of the nasal drops continued to persist even after the treatment had been discontinued. However, the scientists caution that administering the drops too soon after a stroke may have a negative effect as it could lead to an increase in the presence of inflammatory cells in the brain.
According to Prof. Marcela Pekna, the lead researcher from U Gothenburg, the advantage of this approach is that there is no longer a need to rush against time. In clinical practice, if this treatment is implemented, it can be provided to all stroke patients, including those who arrive at the hospital beyond the optimal time for thrombolysis or thrombectomy. Additionally, even individuals who still experience disability after clot removal have the potential to improve with this treatment.
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